When two sisters, Lisa (Mandy Moore) and Kate (Claire Holt), decide to take a trip to Mexico, it quickly becomes a trip to remember. After meeting two locals, the girls are asked if they’d like to try cage diving to get up close with nature’s perfect predator – the Great White Shark. Though hesitant at first, Lisa is persuaded by the locals and her sister to give it a try.

But the experience of a lifetime soon becomes a nightmare for the sisters as their cage detaches from their boat and sinks 47 meters to the ocean floor. With their oxygen tanks running dangerously low, the girls are not alone as they come face to face with several hungry Great White Sharks.